NFL Week 10 Picks & Predictions 2026: Game-by-Game Winners
NFL Week 10 picks 2026 name a winner in all 14 games, from Commanders at Giants on Thursday to Chargers at Ravens on Monday night.
The Bears, Broncos, Eagles and Buccaneers are on bye. Patriots vs Lions kicks off in Munich at 9:30 AM ET on Sunday.
These are fan predictions for entertainment only.
The picks went 15-0 in Week 9, the first perfect week of the season, and the 2026 record is 95-39-1. The Bills and 49ers lead the league at 7-1. The Chargers are 0-8.
Quarterback news shapes this week. Patrick Mahomes is working back from an elbow injury, Minnesota has no named starter with Kyler Murray out, and Jacoby Brissett is expected to start for Baltimore on Monday night.
In This Article10 sections · tap to jump
Who Wins Thursday Night Football in Week 10?
Washington Commanders at New York Giants, 8:15 PM ET on Prime Video
Washington is 2-5-1 after a 20-13 loss to the Rams. Jayden Daniels threw for 274 yards, but Myles Garrett had 3 sacks and a forced fumble.
The Commanders are thin up front. Defensive tackles Javon Kinlaw and Daron Payne are both out for the season.
The Giants are 5-2-1 and lead the NFC East after a 19-11 win in Philadelphia. Arvell Reese had 3 sacks, and Jameis Winston threw the go ahead touchdown to Isaiah Likely.
J.J. McCarthy hurt his hip in that game, but coach John Harbaugh expects him to play. Cam Skattebo (hamstring) should be ready. The Giants at home on a short week are the pick.
Pick: Giants
Who Wins the Week 10 Munich Game?
New England Patriots vs Detroit Lions, 9:30 AM ET on FOX, Allianz Arena, Munich
New England is 5-4 after a 45-27 loss to Green Bay. Drake Maye threw for 299 yards and 3 touchdowns, with 3 interceptions.
Rhamondre Stevenson, Will Campbell and Carlton Davis III all left that game with knee injuries. A.J. Brown is uncertain for the trip.
Detroit is 6-2 and the designated home team after a 19-9 win in Miami. Jahmyr Gibbs scored, and Jake Bates kicked 4 field goals.
The Lions also traded for safety Andre Cisco from the Jets. Detroit is healthier and deeper.
Pick: Lions
What are the NFL Week 10 Picks for the 1:00 PM ET Games?
Kansas City Chiefs at Atlanta Falcons (CBS)
Kansas City is 6-2 after a 35-12 win over the Jets. Patrick Mahomes threw 2 touchdowns to Kenneth Walker III, who scored 3 times.
Mahomes hurt his throwing elbow on a sack. An MRI showed no major injury, and Andy Reid called the news more positive than negative. Justin Fields is next in line.
Atlanta is 3-6 after a 34-17 loss to Cincinnati in Madrid. Michael Penix Jr. threw for 162 yards, and the Falcons traded safety Jessie Bates III to Jacksonville. Kansas City has the better roster.
Pick: Chiefs
Miami Dolphins at Indianapolis Colts (CBS)
Miami is 1-7 after a 19-9 loss to Detroit. Malik Willis threw for 128 yards and an interception and has a groin injury. Coach Jeff Hafley expects to know more Wednesday.
Indianapolis is 2-7 after a 27-23 loss to Dallas that ended on a late interception. Daniel Jones threw for 180 yards and a touchdown.
The Colts are open to offers for Jonathan Taylor before the deadline. Home field gives Indianapolis the edge.
Pick: Colts
Buffalo Bills at New York Jets (CBS)
Buffalo is 7-1 after a 23-6 win in Minnesota. James Cook ran 31 times for 107 yards and a touchdown, and the Bills held the ball for 42:32.
Receiver Joshua Palmer (hamstring) went on injured reserve.
The Jets are 2-7 after a 35-12 loss in Kansas City. Geno Smith threw for 165 yards and was sacked 5 times. Garrett Wilson missed that game with a concussion, and Will McDonald IV has asked for a trade.
Pick: Bills
Houston Texans at Cleveland Browns (FOX)
Houston is 3-5 after a 44-22 rout of the Chargers. C.J. Stroud threw for 384 yards and 5 touchdowns, and the pass rush sacked Justin Herbert 8 times.
Kayshon Boutte had 125 yards and 2 scores, and Tank Dell added 105 yards and a touchdown.
Cleveland is 5-4 after a 23-22 overtime loss in New Orleans. Shedeur Sanders threw for 297 yards and 2 touchdowns before a late 2 point try failed.
Deshaun Watson has cleared the concussion protocol, and reports say he will start. This is the upset pick: Stroud is playing his best football of the season.
Pick: Texans
Jacksonville Jaguars at Tennessee Titans (FOX)
Jacksonville is 6-2 after a 33-10 win in Baltimore. The Jaguars added defensive tackles Jordan Davis and Davon Godchaux and safety Jessie Bates III before the deadline.
Tennessee is 1-7 and comes off its bye. The Titans traded Jeffery Simmons to Chicago, and Cam Ward faces a loaded Jaguars front.
Pick: Jaguars
Minnesota Vikings at Green Bay Packers (FOX)
Minnesota is 6-2 after a 23-6 loss to Buffalo. Carson Wentz went 8 of 25 for 81 yards with 2 interceptions before Max Brosmer replaced him.
Kyler Murray (hamstring) is week to week, and the Vikings have not named a starter as they explore the trade market.
Green Bay is 6-3 after a 45-27 win in New England. Jordan Love threw for 372 yards and 3 touchdowns, with Matthew Golden at 164 yards and Christian Watson at 171.
Josh Jacobs has a fractured finger, and Matt LaFleur hopes he can play through it. Love at Lambeau is the pick.
Pick: Packers
Carolina Panthers at New Orleans Saints (FOX)
Carolina is 3-5 after a 26-21 loss to Denver. Bryce Young threw for 276 yards and 3 touchdowns, but a strip sack with 1:24 left ended the comeback.
New Orleans is 3-5 after a 23-22 overtime win over Cleveland. Tyler Shough threw the winning 15 yard touchdown to Juwan Johnson, though center Erik McCoy hurt his biceps.
The Saints at home in a division game is the closest call of the week.
Pick: Saints
What are the NFL Week 10 Picks for the Late Games?
Los Angeles Rams at Arizona Cardinals, 4:05 PM ET (CBS)
The Rams are 5-4 after a 20-13 win in Washington. Puka Nacua caught 14 passes for 150 yards and a touchdown, then hurt his knee on the final play.
Sean McVay says Nacua has MCL and PCL sprains plus turf toe and is likely headed to injured reserve. Guard Steve Avila has a hamstring injury.
Arizona is 3-6 after a 17-3 loss in Seattle, where Gardner Minshew threw for 166 yards. Matthew Stafford and Myles Garrett give the Rams the edge even without Nacua.
Pick: Rams
Seattle Seahawks at Las Vegas Raiders, 4:05 PM ET (CBS)
Seattle is 5-4 after a 17-3 win over Arizona. Drew Lock threw for 175 yards, and AJ Barner scored twice.
Sam Darnold (quad) is out again, so Lock starts after a good exam on his oblique. Guard Quenton Nelson needs a minor knee procedure.
Las Vegas is 4-5 after a 38-17 loss in San Francisco. Kirk Cousins threw 3 interceptions, including a pick six. A Seattle defense that allowed 3 points last week gets the call.
Pick: Seahawks
San Francisco 49ers at Dallas Cowboys, 4:25 PM ET (FOX)
San Francisco is 7-1 after a 38-17 win over Las Vegas. Brock Purdy threw 2 touchdowns, and Fred Warner forced one fumble and recovered another.
Mike Evans (Achilles) and Deebo Samuel (hamstring) missed that game. Gracen Halton is out for the season with a broken ankle.
Dallas is 4-5 after a 27-23 win in Indianapolis. Dak Prescott threw for 335 yards and 2 touchdowns, and CeeDee Lamb had 195 receiving yards.
George Pickens (hamstring) missed Week 9 and is uncertain, and Jake Ferguson hurt his knee. The 49ers are the more complete team.
Pick: 49ers
Who Wins Sunday Night Football in Week 10?
Pittsburgh Steelers at Cincinnati Bengals, 8:20 PM ET on NBC and Peacock
Pittsburgh is 6-2 and comes off its bye. Before the break, the Steelers beat Cleveland 27-6 with 8 sacks of Deshaun Watson.
Cincinnati is also 6-2 after a 34-17 win over Atlanta in Madrid, its fourth straight win. Joe Burrow went 24 of 29 for 271 yards and 3 touchdowns, and Ja’Marr Chase had 155 yards.
First place in the AFC North is on the line. Burrow at home is the pick.
Pick: Bengals
Who Wins Monday Night Football in Week 10?
Los Angeles Chargers at Baltimore Ravens, 8:15 PM ET on ESPN
The Chargers are 0-8 after a 44-22 loss to Houston. Justin Herbert hurt his left middle finger, but imaging showed no fracture and he says it should not be an issue.
Ladd McConkey (back) missed that game.
Baltimore is 4-5 after four straight losses. Jacoby Brissett, acquired from Arizona, is expected to start with Lamar Jackson on injured reserve after a thumb injury that needs surgery.
Kyle Hamilton hurt his hip on Thursday but is not expected to miss time. The Ravens have had 11 days to prepare, and the Chargers have not won yet.
Pick: Ravens
NFL Week 10 Picks 2026: Quick Recap Table
| Date | Matchup | Time (ET) | TV | Pick |
|---|---|---|---|---|
| Thu, Nov 12 | Commanders (2-5-1) at Giants (5-2-1) | 8:15 PM | Prime Video | Giants |
| Sun, Nov 15 | Patriots (5-4) vs Lions (6-2), Munich | 9:30 AM | FOX | Lions |
| Sun, Nov 15 | Chiefs (6-2) at Falcons (3-6) | 1:00 PM | CBS | Chiefs |
| Sun, Nov 15 | Dolphins (1-7) at Colts (2-7) | 1:00 PM | CBS | Colts |
| Sun, Nov 15 | Bills (7-1) at Jets (2-7) | 1:00 PM | CBS | Bills |
| Sun, Nov 15 | Texans (3-5) at Browns (5-4) | 1:00 PM | FOX | Texans |
| Sun, Nov 15 | Jaguars (6-2) at Titans (1-7) | 1:00 PM | FOX | Jaguars |
| Sun, Nov 15 | Vikings (6-2) at Packers (6-3) | 1:00 PM | FOX | Packers |
| Sun, Nov 15 | Panthers (3-5) at Saints (3-5) | 1:00 PM | FOX | Saints |
| Sun, Nov 15 | Rams (5-4) at Cardinals (3-6) | 4:05 PM | CBS | Rams |
| Sun, Nov 15 | Seahawks (5-4) at Raiders (4-5) | 4:05 PM | CBS | Seahawks |
| Sun, Nov 15 | 49ers (7-1) at Cowboys (4-5) | 4:25 PM | FOX | 49ers |
| Sun, Nov 15 | Steelers (6-2) at Bengals (6-2), SNF | 8:20 PM | NBC, Peacock | Bengals |
| Mon, Nov 16 | Chargers (0-8) at Ravens (4-5), MNF | 8:15 PM | ESPN | Ravens |
Kickoff times and TV were checked against the NFL.com Week 10 schedule on November 10, 2026. Records are through Week 9.
- Home and road: 7 home teams, 7 road teams.
- Upset: Texans over Browns.
- Strongest calls: Bills over Jets, Jaguars over Titans and Lions over Patriots.
- Closest calls: Panthers at Saints, Seahawks at Raiders and Steelers at Bengals.
Running a pool? Fill in the free printable NFL Week 10 pick’em sheet. See where every team stands in the NFL power rankings and check all 32 dates in the NFL bye weeks guide.
How Did the Week 9 Picks Do?
The picks went 15-0 in Week 9: Jaguars, Bengals, Saints, Broncos, Chiefs, Lions, Cowboys, Giants, Rams, Texans, 49ers, Packers, Seahawks, Bears and Bills.
The Saints upset pick won 23-22 in overtime when Cleveland’s 2 point try failed. The Bears beat Tampa Bay 27-24 on a last second field goal despite 4 Caleb Williams interceptions. The season record is 95-39-1.
Which Injuries Shape the NFL Week 10 Picks?
- Quarterbacks: Patrick Mahomes (KC, elbow) has a good chance to play. Kyler Murray (MIN, hamstring) is week to week with no starter named. Jacoby Brissett is expected to start for Baltimore, and Deshaun Watson is expected back for Cleveland.
- More quarterbacks: Sam Darnold (SEA) is out, so Drew Lock starts. J.J. McCarthy (NYG, hip) and Justin Herbert (LAC, finger) are expected to play. Malik Willis (MIA, groin) is one to watch.
- Out or likely out: Puka Nacua (LAR, knee, likely injured reserve), Mike Evans (SF, Achilles).
- Questionable or uncertain: Deebo Samuel (SF), A.J. Brown and Rhamondre Stevenson (NE), Josh Jacobs (GB, finger), George Pickens and Jake Ferguson (DAL), Xavier Worthy (KC), Garrett Wilson (NYJ, concussion), Ladd McConkey (LAC), Steve Avila (LAR).
- Season over or on injured reserve: Lamar Jackson and Tyler Huntley (BAL), Jaxson Dart (NYG), Gracen Halton (SF), Javon Kinlaw and Daron Payne (WAS), Joshua Palmer (BUF).
- Trades: Jacksonville added Jordan Davis, Jessie Bates III and Davon Godchaux. Detroit added Andre Cisco, and Baltimore added Jacoby Brissett.
The trade deadline is Tuesday, November 10 at 4:00 PM ET, and this page is updated if a deal changes a pick. Follow every move in the NFL.com trade deadline tracker.
Practice reports start Wednesday. Final injury designations for Sunday games come Friday, and for Monday night on Saturday.
NFL Week 10 Picks 2026 FAQ
What are the NFL Week 10 picks for 2026?
The winners are the Giants, Lions, Chiefs, Colts, Bills, Texans, Jaguars, Packers, Saints, Rams, Seahawks, 49ers, Bengals and Ravens.
What is the upset pick for NFL Week 10?
Texans over Browns. C.J. Stroud threw for 384 yards and 5 touchdowns in Week 9, and Cleveland is coming off an overtime loss.
How many games are in NFL Week 10 2026?
Fourteen. The Chicago Bears, Denver Broncos, Philadelphia Eagles and Tampa Bay Buccaneers are on bye.
When does NFL Week 10 start and end in 2026?
Week 10 starts Thursday, November 12 with Commanders at Giants at 8:15 PM ET on Prime Video and ends Monday, November 16 with Chargers at Ravens at 8:15 PM ET on ESPN.
What time is the Week 10 Munich game?
Patriots vs Lions kicks off at 9:30 AM ET on Sunday, November 15 at the Allianz Arena in Munich, on FOX. Detroit is the home team.
Is Patrick Mahomes playing in Week 10?
He has a good chance. An MRI on his throwing elbow showed no major injury, and Andy Reid called the news more positive than negative.
Who starts at quarterback for the Ravens on Monday night?
Jacoby Brissett is expected to start against the Chargers. Lamar Jackson is on injured reserve with a thumb injury that needs surgery.
What is the NFL picks record on this site in 2026?
The picks went 15-0 in Week 9, the first perfect week of the season, and the 2026 record is 95-39-1.
NFL Week 10 picks 2026 back the Bills, Jaguars and Lions as the strongest calls, with Texans over Browns as the upset. Steelers at Bengals on Sunday night decides first place in the AFC North.
Next, check the Week 9 picks to see how every game played out, or the NFL Week 10 schedule 2026 for kickoff times and channels.
